A GENETIC AND VIRULENCE CHARACTERIZATION OF BRAZILIAN STRAINS OF MYCOPLASMA HYOPNEUMONIAE


Characterization of 3-Hydroxyisobutyryl-Coa Hydrolase (HIBCH) Deficiency in Bahrain: A Retrospective Cohort Study

Background: 3-Hydroxyisobutyryl-CoA hydrolase (HIBCH) deficiency is a rare inborn error of valine catabolism associated with progressive neurological impairment.This retrospective cohort study aimed to characterize the clinical, biochemical, genetic, and respiratory chain profiles of HIBCH Top deficiency patients in Bahrain.Methods: Eight HIBCH def

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Adult ADHD: Risk Factor for Dementia or Phenotypic Mimic?

Attention-deficit hyperactivity disorder (ADHD) has historically been considered a disorder of childhood and adolescence.However, it is now recognized that ADHD symptoms persist into adulthood in up to 60% of individuals.Some of the cognitive symptoms that characterize ADHD (inability Cutouts to provide sustained attention or mental effort, difficu

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Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O6-Alkylguanine-DNA Alkyltransferase Activity

Human O6-alkylguanine-DNA alkyltransferase (hAGT) is a DNA repair protein that reverses the effects of alkylating agents Headband by removing DNA adducts from the O6 position of guanine.Here, we developed a real-time fluorescence hAGT activity assay that is based on the detection of conformational changes of the thrombin-binding aptamer (TBA).The q

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